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Thioflavine S

Thioflavine S

Class: Thiazole
Ionisation: Acid

Chemical structure of Thioflavine S

Common Name: Thioflavine S
Suggested Name: Thioflavine S
Other Names:

C.I. Number: 49010
C.I. Name: Direct yellow 7
Color: Yellow
Solubility Aqueous: Very
Solubility Ethanol: Very
Absorption Maximum: 374
Empirical Formula:
Formula Weight:


The structural formula above was located via the Internet, and is of the major component of the dye, according to Wu and coworkers. It is a fluorescent dye and is a mixture, one component of which demonstrates amyloid. Conn states that thioflavine S is made from primuline by methylation and sulphonation.


  1. R. D. Lillie.
    Conn’s Biological Stains
    Williams & Wilkins, Baltimore, MD., U.S.A.
  2. Wu, C., Wei, J.. Gao. Y and Wang. Y.,
    Dibenzothiazoles as novel amyloid-imaging agents,
    Elsevier, U.S.A.