Histological Staining Theory

Basic Chemistry

The science underlying histological staining is rooted in principles of basic chemistry. Explore the resources below to learn more.

Explore this interactive tool to learn more about the histological application of elements.
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Learn how to apply the basics of chemistry to various staining components from the resources below.

Differentiation involves removing removing excess dye from tissues to accentuate a structure which retains the dye applied.
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Metachromasia is a phenomenon observed when a solution of a single dye stains tissue elements in two colors.
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